Optics in Medicine

Dr. Kleinsasser, 5 ECTS

• Biological Systems
• Trunk System
• Nervous System
• Respiration
• Circulation
• Heart
• Digestion
• Neuroscience
• Functional cardiology
• Advanced endoscopy
• Advanced neuroimaging

Students learn to

• describe relevant structures of the human anatomy and basic physiological processes
• understand features of biological systems when applying optical technologies to them
• describe exemplarily applications of optical technologies in medicine

Dr. Klämpfl, 5 ECTS

• Repetition of important topics of optics
• Scattering of light
• Basics of laser tissue interaction
• Diagnostics applications of Light and lasers
• Therapeutics applications of light and lasers
• Theoretical and practical exercises

Comment: The two courses about Magnetic Resonance Imaging are not offered in the order which would be ideal for MAOT students, but in opposite order. Students with some prior knowledge in the field might consider to join Magnetic Resonance Imaging 2 directly. Other options are: attending part one during the fundamental courses in the first semester; starting with the part one in the third semester (maybe only attending part one); working on part 1 based on recordings from previous semesters and only attend part 2 in the actual course.

Prof. Dr. Fredrik Laun, 5 ECTS

• Echo-planar imaging
• Functional magnetic resonance imaging
• Parallel imaging: SENSE
• Parallel imaging: GRAPPA
• Balanced steady state sequences
• UHF MRI and non-proton MRI
• Multiple RF-pulses – coherence pathways – time-of-flight MRI
• Flow-motion
• Perfusion – diffusion
• Diffusion: Susceptibility weighted imaging & Quantitative Susceptibility Mapping

Dr. Klämpfl, 5 ECTS

• Selected topics of optics
• Light sources for medical applications and medical engineering
• Optical components and systems for medical engineering
• Interaction mechanisms of laser and biological tissue
• Photonics in diagnostics
• Photonics in therapeutics

Prof. Dr. Friedrich, PD Dr. Schürmann, 5 ECTS

• Application of optical methods in the field of cell biology and medicine
• Microscopy: Basic concepts, methods to enhance contrast, optical resolution and limits, components and setup of light microscopes, fluorescence microscopy
• Applications of fluorescence microscopy in life sciences, methods for labeling of biological structures and cellular processes´
• Epi-fluorescence, confocal and multiphoton microscopy, concepts and application examples
• Optical endoscopy and endomicroscopy in research and clinics
• Super-resolution microscopy, concepts and applications for optical Imaging beyond the diffraction Limit of Resolution

Prof. Dr. Fredrik Laun, 5 ECTS

• The basics of image formation
• Some basic pulse sequences
• About contrast generation
• A bit about artefacts
• A bit about acceleration techniques

Prof. Sandoghdar, Dr. Möckl 5 ECTS

In winter term 2022/23 the course for this module is called „Microscopy approaches to study biological systems„

Microscopy has become an indispensable tool to investigate biological systems – from viruses to whole animals. In this seminar, we will explore this fascinating research area by studying and discussing key publications from the field. Each participant is assigned to a couple of important publications that employed a microscopy approach to study a biological question in a creative, impactful, and instructive way. Examples include optical microscopy methods such as light-sheet microscopy, super-resolution approaches, and scattering-based techniques; electron microscopy; or mass spectrometry imaging. Furthermore, important image analysis strategies will be considered. Each participant will discuss the publications with the seminar instructors and subsequently present the approach and the key findings to the whole seminar.